next generation sequencing data congress

A tale of three next generation sequencing platforms: comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers., azide free, Blogging, elisa, Goat, Hamster, Mammal, Mink, Mouse, Multiplexed shotgun genotyping for rapid and efficient genetic mapping., NGS QC Toolkit: a toolkit for quality control of next generation sequencing data., Opossum, Orangutan, pcr, Pig, Pigeon, Plant, Rat, Yeast

Phylogenetic microbiota profiling in fecal samples depends on combination of sequencing depth and choice of NGS analysis method.

The human intestine microbiota is nicely established as an essential issue in well being and illness. Fecal pattern microbiota are sometimes analyzed as a proxy for intestine microbiota, and characterised with respect to their composition profiles. Modern approaches make use of complete genome shotgun next-generation sequencing as the premise for these analyses. Sequencing depth in addition to choice of next-generation sequencing information analysis methodology represent two essential interacting methodological elements for such an method. In this research, we used 200 million sequence learn pairs from one fecal pattern for evaluating totally different taxonomy classification strategies, utilizing default and custom-made reference databases, at totally different sequencing depths.

A mock group information set with identified composition was used for validating the classification strategies. Results counsel that sequencing past 60 million learn pairs doesn’t appear to enhance classification. The phylogeny prediction sample, when utilizing the default databases and the consensus database, gave the impression to be comparable for all three strategies. Moreover, these strategies predicted moderately totally different species. We conclude that the choice of sequencing depth and classification methodology has essential implications for taxonomy composition prediction.

A multi-method-consensus method for sturdy intestine microbiota NGS analysis is really helpful. Clinical genetic testing to diagnose germline mutations typically requires blood pattern or saliva smear from a cancer-affected particular person. This guidelines out testing in households when cancer-affected people are deceased. We explored the use of a next-generation sequencing (NGS) platform to diagnose germline pathogenic mutations from tumors.Archival tumors (ovarian = 26, breast = 25, others = 9) have been retrieved from 60 most cancers sufferers who’ve undergone multi-gene panel blood testing. Genomic DNA was extracted and sequenced for BRCA1/2 utilizing a NGS platform.

41/60 specimens have been sequenced for five different genes. Tumor testing and outcomes interpretation have been carried out blinded to the blood take a look at outcome.All 38 sufferers with no BRCA1/2 mutations on blood testing have been appropriately examined adverse on tumor. Next era sequencing (NGS) applied sciences present an more and more essential avenue for detecting identified viruses, and for locating novel viruses current in medical or environmental samples. Several computational pipelines succesful of figuring out and classifying viral sequences in NGS information have been developed and used to seek for viruses in human or animal samples, microbiomes, and in varied environments.

In this evaluation we summarize the totally different approaches used to find out viral presence in sequence information. Strategies for avoiding confounding elements reminiscent of bodily contamination and computational artifacts that result in false virus identification are mentioned. The software of these methodologies to most cancers information units has led to essential insights on viruses each as drivers of and biomarkers for particular tumors.

Proteogenomics: From next-generation sequencing (NGS) and mass spectrometry-based proteomics to precision medication.

One of the best-established space inside multi-omics is proteogenomics, whereby the underpinning applied sciences are next-generation sequencing (NGS) and mass spectrometry (MS). Proteogenomics has contributed considerably to genome (re)-annotation, whereby novel coding sequences (CDS) are recognized and confirmed. By incorporating in-silico translated genome variants in protein database, single amino acid variants (SAAV) and splice proteoforms could be recognized and quantified at peptide stage.

The software of proteogenomics in most cancers analysis probably allows the identification of patient-specific proteoforms, in addition to the affiliation of the efficacy or resistance of most cancers remedy to totally different mutations. Here, we talk about how NGS/TGS information are analyzed and included into the proteogenomic framework. These sequence information primarily originate from complete genome sequencing (WGS), complete exome sequencing (WES) and RNA-Seq. Practical concerns for standardization of these variables are offered to facilitate correct, dependable, and reproducible NGS-based molecular characterization of tumors, finally informing prognosis and guiding remedy.

We clarify two main methods for sequence analysis i.e., de novo meeting and reads mapping, adopted by building of custom-made protein databases utilizing such information. Besides, we additionally elaborate on the procedures of spectrum to peptide sequence matching in proteogenomics, and the connection between database dimension on the false discovery charge (FDR). Finally, we talk about the most recent improvement in proteogenomics-assisted precision oncology and additionally challenges and alternatives in proteogenomics analysis.

Preanalytic Variables and Tissue Stewardship for Reliable Next-Generation Sequencing (NGS) Clinical Analysis.

An enduring objective of personalised medication in most cancers is the flexibility to establish sufferers who’re doubtless to reply to particular therapies. Our rising understanding of the biology and molecular signatures of particular person tumor varieties has facilitated the identification of predictive biomarkers and has led to an rising quantity of diagnostic checks to be carried out, typically as serial and distinct assays on restricted tumor specimens. In this text, every step in the tissue journey is printed, with particular focus on preanalytic variables that may affect NGS outcomes.

ELISA Microplate Washer, Manual
MPW-60	Alpha Diagnostics	1	EUR 1877

Microplate Sealer
abx292001-100Units	Abbexa	100 Units	EUR 63
Shipped within 1-3 working days.

Holder f/ ELISA microplate&skirted PCR microplate, accessory for AgileMixer?
ACT-AVM3000-4	ACTGene		EUR 101

ELISA Microplate Washer Automated, programmable
MPW-30	Alpha Diagnostics	1	EUR 5165

Digital Microplate Shaker
abx725004-1Unit	Abbexa	1 Unit	EUR 554
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4 position Microplate Shaker
abx725017-1Unit	Abbexa	1 Unit	EUR 798
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Microplate Swing-Out Centrifuge
abx725026-1Unit	Abbexa	1 Unit	EUR 1476
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48 WELL PCR MICROPLATE
PCR-48-C	CORNING	10/pk	EUR 102
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen

ELISA Microplate Washer Head (8 channel) replacement
MPW-WH-1	Alpha Diagnostics	1	EUR 354

Filter for Accuris Microplate Reader
MR9600-340	BenchMark	1 PC	EUR 239
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MR9600-380	BenchMark	1 PC	EUR 246.25
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MR9600-405	BenchMark	1 PC	EUR 201.3
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MR9600-415	BenchMark	1 PC	EUR 201.3
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MR9600-420	BenchMark	1 PC	EUR 201.3
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MR9600-450	BenchMark	1 PC	EUR 201.3
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MR9600-470	BenchMark	1 PC	EUR 201.3
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MR9600-490	BenchMark	1 PC	EUR 201.3
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MR9600-492	BenchMark	1 PC	EUR 201.3
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MR9600-510	BenchMark	1 PC	EUR 201.3
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MR9600-520	BenchMark	1 PC	EUR 201.3
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MR9600-532	BenchMark	1 PC	EUR 201.3
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MR9600-540	BenchMark	1 PC	EUR 201.3
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MR9600-546	BenchMark	1 PC	EUR 201.3
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MR9600-560	BenchMark	1 PC	EUR 201.3
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MR9600-562	BenchMark	1 PC	EUR 201.3
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MR9600-570	BenchMark	1 PC	EUR 201.3
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MR9600-578	BenchMark	1 PC	EUR 201.3
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MR9600-590	BenchMark	1 PC	EUR 201.3
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MR9600-595	BenchMark	1 PC	EUR 201.3
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MR9600-600	BenchMark	1 PC	EUR 201.3
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MR9600-620	BenchMark	1 PC	EUR 201.3
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MR9600-630	BenchMark	1 PC	EUR 201.3
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MR9600-646	BenchMark	1 PC	EUR 201.3
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MR9600-650	BenchMark	1 PC	EUR 201.3
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MR9600-663	BenchMark	1 PC	EUR 201.3
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MR9600-700	BenchMark	1 PC	EUR 201.3
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MR9600-750	BenchMark	1 PC	EUR 201.3
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24 WELL PCR MICROPLATE. CLEAR
PCR-24-C	CORNING	10/pk	EUR 73
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen

32 WELL PCR MICROPLATE. CLEAR
PCR-32-C	CORNING	10/pk	EUR 88
Description: PCR Plates & Tubes; PCR Strip Tubes and Strip Caps - Axygen

384 WELL PCR MICROPLATE. CLEAR
PCR-384-C	CORNING	10/pk	EUR 183
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL CLEAR PCR MICROPLATE
PCR-96-C	CORNING	10/pk	EUR 145
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

EpiMag 96-Well Microplate (5/pack)
Q10003	EpiGentek	5/pack	EUR 113.8
Description: fast delivery possible

384 WELL BLACK RIGI PLATE PCR MICROPLATE
PCR-384-RGD-BK	CORNING	20/pk	EUR 488
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL CLEAR PCR MICROPLATE. PRE-STERILIZED
PCR-96-C-S	CORNING	10/pk	EUR 183
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL CLEAR, FLAT TOP PCR MICROPLATE
PCR-96-FLT-C	CORNING	25/pk	EUR 202
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

384 WELL CLEAR RIGI PLATE PCR MICROPLATE. CLEAR
PCR-384-RGD-C	CORNING	20/pk	EUR 459
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

MicroPlate MicroCentrifuge with rotor and plate carriers, 115V
BCM1749	Bio Basic	1 pcs, 1 UNIT	EUR 949.19
Product category: Benchtop Equipment/Centrifuges/Microplate

ELISA Microplate Reader (compact, 8 channel, automated, programmable) with 4 filters & ELISA reader software
MPR-404	Alpha Diagnostics	1	EUR 5531

ELISA Microplate Reader (compact, 8 channel, automated, programmable) with 6 filters & ELISA reader software
MPR-406	Alpha Diagnostics	1	EUR 5896

96 WELL CLEAR LOW PROFILE PCR MICROPLATE FOR ABI
PCR-96-LP-AB-C	CORNING	25/pk	EUR 388
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL WHITE LOW PROFILE PCR MICROPLATE FOR AB
PCR-96-LP-AB-W	CORNING	25/pk	EUR 388
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL CLEAR LOW PROFILE, FLAT TOP PCR MICROPLATE
PCR-96-LP-FLT-C	CORNING	25/pk	EUR 230
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL WHITE LOW PROFILE, FLAT TOP PCR MICROPLATE
PCR-96-LP-FLT-W	CORNING	25/pk	EUR 230
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

ELISA Microplate Washer Automated (#MPW-30) bottle set (3 bottles and cap assembly)
MPW-30-SET	Alpha Diagnostics	1	EUR 408

MICROPLATE, 1536 WELL, COC, BLACK, NBS, NO LID, NONSTERILE, BULK
4567	CORNING	10/pk	EUR 1005
Description: Assay; Barcoded - 1536 Well

MICROPLATE, 1536 WELL, COC, WHITE, NBS, NO LID, NONSTERILE, BULK
4572	CORNING	10/pk	EUR 1005
Description: Assay; Barcoded - 1536 Well

TW,96WL,HTS,RECEIVER MICROPLATE,TCT,W/LID,S,10/10
3382	CORNING	10/pk	EUR 169
Description: Permeable Support; HTS Transwell

MICROPLATE, 1536 WELL, COC, BLACK, NOT TREATED, NO LID, NONSTERILE, BULK
4565	CORNING	10/pk	EUR 697
Description: Assay; Barcoded - 1536 Well

MICROPLATE, 1536 WELL, COC, BLACK , TC TREATED, NO LID, STERILE, BULK
4566	CORNING	10/pk	EUR 790
Description: Assay; Barcoded - 1536 Well

MICROPLATE, 1536 WELL, COC,WHITE, NOT TREATED, NO LID, NONSTERILE, BULK
4570	CORNING	10/pk	EUR 697
Description: Assay; Barcoded - 1536 Well

MICROPLATE, 1536 WELL, COC, WHITE , TC TREATED, NO LID, STERILE, BULK
4571	CORNING	10/pk	EUR 790
Description: Assay; Barcoded - 1536 Well

Helixyte™ Green Fluorimetric dsDNA Quantitation Kit Optimized for Microplate Readers
17650	AAT Bioquest	200 Tests	EUR 219
R-phrase: R20, R21, R68 H-Phrase: H303, H313, H340 Symbol for dangerous compounds: T UNSPEC Code: 41116134

StrandBrite™ Green Fluorimetric RNA Quantitation Kit Optimized for Microplate Readers
17655	AAT Bioquest	1000 Tests	EUR 306
R-phrase: R20, R21, R68 H-Phrase: H303, H313, H340 Symbol for dangerous compounds: T UNSPEC Code: 41116134

96 WELL HALF SKIRT AUTOMATION COMPATIBLE PCR MICROPLATE, NON-STERILE, BLUE
PCR-96-HS-AC-B	CORNING	10/pk	EUR 170
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL HALF SKIRT AUTOMATION COMPATIBLE PCR MICROPLATE, NON-STERILE, CLEAR
PCR-96-HS-AC-C	CORNING	10/pk	EUR 170
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL HALF SKIRT AUTOMATION COMPATIBLE PCR MICROPLATE, NON-STERILE, GREEN
PCR-96-HS-AC-G	CORNING	10/pk	EUR 170
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL HALF SKIRT AUTOMATION COMPATIBLE PCR MICROPLATE, NON-STERILE, RED
PCR-96-HS-AC-R	CORNING	10/pk	EUR 170
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL HALF SKIRT AUTOMATION COMPATIBLE PCR MICROPLATE, NON-STERILE, WHITE
PCR-96-HS-AC-W	CORNING	10/pk	EUR 170
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL HALF SKIRT AUTOMATION COMPATIBLE PCR MICROPLATE, NON-STERILE, YELLOW
PCR-96-HS-AC-Y	CORNING	10/pk	EUR 170
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

MICROPLATE, 96 WELL, POLYPROPYLENE, 500 µL, CLEAR, ROUND BOTTOM, NONSTERILE, BULK
P-96-450R-C	CORNING	10/pk	EUR 110
Description: Deep Well/Assay Plates - Axygen; Assay/Other - Axygen

MICROPLATE, 96 WELL, POLYPROPYLENE, 500 µL, CLEAR, ROUND BOTTOM, STERILE, BULK
P-96-450R-C-S	CORNING	10/pk	EUR 138
Description: Deep Well/Assay Plates - Axygen; Assay/Other - Axygen

MICROPLATE, 96 WELL, POLYPROPYLENE, 500 µL, BLUE, V-BOTTOM, NONSTERILE, BULK
P-96-450V-B	CORNING	10/pk	EUR 118
Description: Deep Well/Assay Plates - Axygen; Assay/Other - Axygen

MICROPLATE, 96 WELL, POLYPROPYLENE, 500 µL, CLEAR, V-BOTTOM, NONSTERILE, BULK
P-96-450V-C	CORNING	10/pk	EUR 114
Description: Deep Well/Assay Plates - Axygen; Assay/Other - Axygen

MICROPLATE, 96 WELL, POLYPROPYLENE, 500 µL, CLEAR, V-BOTTOM, STERILE, BULK
P-96-450V-C-S	CORNING	10/pk	EUR 132
Description: Deep Well/Assay Plates - Axygen; Assay/Other - Axygen

MICROPLATE, 96 WELL, POLYPROPYLENE, 500 µL, YELLOW, V-BOTTOM, NONSTERILE, BULK
P-96-450V-Y	CORNING	10/pk	EUR 118
Description: Deep Well/Assay Plates - Axygen; Assay/Other - Axygen

MICROPLATE, 1536 WELL, COC, BLACK CLEAR BOTTOM, NT, NO LID, STERILE, BULK
4560	CORNING	20/pk	EUR 1439
Description: Assay; Barcoded - 1536 Well

OPTIONAL HEAD FOR ONE MICROPLATE OR 64X0.2ML TUBES OR 8X0.2ML TUBE STRIPS
480102	CORNING	1/pk	EUR 63
Description: Lab Equipment; Shakers & Mixers

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, FLAT BOTTOM, MEDIUM BINDING, NO LID, NONSTERILE, BULK
9017	CORNING	25/pk	EUR 179
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, FLAT BOTTOM, HIGH BINDING, NO LID, NONSTERILE, BULK
9018	CORNING	25/pk	EUR 185
Description: Assay; EIA/RIA - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, FLAT BOTTOM, TC-TREATED, WITH LID, STERILE, BULK
3598	CORNING	5/pk	EUR 241
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, FLAT BOTTOM, TC-TREATED, WITH LID, STERILE, BULK
3628	CORNING	20/pk	EUR 214
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, V-BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
3897	CORNING	25/pk	EUR 208
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, WHITE, FLAT BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
3912	CORNING	25/pk	EUR 293
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, BLACK, FLAT BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
3915	CORNING	25/pk	EUR 346
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, BLACK, FLAT BOTTOM, TC-TREATED, WITH LID, STERILE, BULK
3916	CORNING	20/pk	EUR 401
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, WHITE, FLAT BOTTOM, TC-TREATED, WITH LID, STERILE, BULK
3917	CORNING	20/pk	EUR 433
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, WHITE, FLAT BOTTOM, HIGH BINDING, NO LID, NONSTERILE, BULK
3922	CORNING	25/pk	EUR 323
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, BLACK, FLAT BOTTOM, HIGH BINDING, NO LID, NONSTERILE, BULK
3925	CORNING	25/pk	EUR 323
Description: Assay; General Assay - 96 Well

SEALING MAT, FOR 384 WELL DEEP WELL MICROPLATE, POLYPROPYLENE, CHEMICAL RESISTANT, NONSTERILE, BULK
3341	CORNING	10/pk	EUR 330
Description: Storage; Storage Mats

MICROPLATE, 96 WELL, POLYPROPYLENE, WHITE, ROUND BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
3355	CORNING	25/pk	EUR 264
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYPROPYLENE, CLEAR, V-BOTTOM, NOT TREATED, NO LID, STERILE, BULK
3357	CORNING	25/pk	EUR 260
Description: Storage; Polypropylene Plates - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, ROUND BOTTOM, TC-TREATED, WITH LID, STERILE, BULK
3358	CORNING	20/pk	EUR 225
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYPROPYLENE, CLEAR, ROUND BOTTOM, NOT TREATED, NO LID, STERILE, BULK
3359	CORNING	25/pk	EUR 256
Description: Storage; Polypropylene Plates - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, ROUND BOTTOM, TC-TREATED, NO LID, STERILE, BULK
3360	CORNING	25/pk	EUR 203
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, FLAT BOTTOM, HIGH BINDING, WITH LID, STERILE, BULK
3361	CORNING	20/pk	EUR 236
Description: Assay; EIA/RIA - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, WHITE, FLAT BOTTOM, TC-TREATED, NO LID, STERILE, BULK
3362	CORNING	25/pk	EUR 380
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYPROPYLENE, CLEAR, V-BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
3363	CORNING	25/pk	EUR 229
Description: Storage; Polypropylene Plates - 96 Well

MICROPLATE, 96 WELL, POLYPROPYLENE, CLEAR, FLAT BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
3364	CORNING	25/pk	EUR 229
Description: Storage; Polypropylene Plates - 96 Well

MICROPLATE, 96 WELL, POLYPROPYLENE, CLEAR, ROUND BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
3365	CORNING	25/pk	EUR 229
Description: Storage; Polypropylene Plates - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, ROUND BOTTOM, HIGH BINDING, NO LID, NONSTERILE, BULK
3366	CORNING	25/pk	EUR 233
Description: Assay; EIA/RIA - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, FLAT BOTTOM, NOT TREATED, WITH LID, STERILE, BULK
3370	CORNING	20/pk	EUR 204
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, ROUND BOTTOM, NOT TREATED, WITH LID, STERILE, BULK
3788	CORNING	20/pk	EUR 225
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, WHITE, ROUND BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
3789A	CORNING	25/pk	EUR 384
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, BLACK, ROUND BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
3792	CORNING	25/pk	EUR 355
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, ROUND BOTTOM, NOT TREATED, NO LID, STERILE, BULK
3795	CORNING	25/pk	EUR 177
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, ROUND BOTTOM, MEDIUM BINDING, NO LID, NONSTERILE, BULK
3797	CORNING	25/pk	EUR 179
Description: Assay; EIA/RIA - 96 Well

MICROPLATE, 1536 WELL, COC, BLACK CLEAR BOTTOM, TC TREATED, NO LID, STERILE, BULK
4561	CORNING	20/pk	EUR 1692
Description: Assay; Barcoded - 1536 Well

Cell Meter™ Phosphatidylserine Apoptosis Assay Kit Blue Fluorescence Optimized for Microplate Readers
22790	AAT Bioquest	100 Tests	EUR 219
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

Cell Meter™ Phosphatidylserine Apoptosis Assay Kit Green Fluorescence Optimized for Microplate Readers
22791	AAT Bioquest	100 Tests	EUR 219
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

Cell Meter™ Phosphatidylserine Apoptosis Assay Kit Red Fluorescence Optimized for Microplate Readers
22792	AAT Bioquest	100 Tests	EUR 219
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

Cell Meter™ Phosphatidylserine Apoptosis Assay Kit Orange Fluorescence Optimized for Microplate Readers
22794	AAT Bioquest	100 Tests	EUR 219
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

Cell Meter™ NIR Mitochondrion Membrane Potential Assay Kit Optimized for Microplate Reader
22803	AAT Bioquest	500 Tests	EUR 219
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

Cell Meter™ Fluorimetric Mitochondrial Superoxide Activity Assay KitOptimized for Microplate Reader
22971	AAT Bioquest	200 Tests	EUR 306
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

384 WELL PCR MICROPLATE FOR ROCHE 480 LIGHT CYCLER, WHITE (INCLUDES SEALING FILM)
PCR-384-LC480-W	CORNING	10/pk	EUR 402
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

384 WELL PCR MICROPLATE FOR ROCHE 480 LIGHT CYCLER, WHITE (NO SEALING FILM)
PCR-384-LC480-W-NF	CORNING	10/pk	EUR 240
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL HALF SKIRT AUTOMATION COMPATIBLE PCR MICROPLATE, NON-STERILE, CLEAR, PRE-BARCODED
PCR-96-HS-AC-C-PBC	CORNING	10/pk	EUR 170
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL PCR MICROPLATE FOR ROCHE 480 LIGHT CYCLER, CLEAR (NO SEALING FILM)
PCR-96-LC480-C-NF	CORNING	10/pk	EUR 199
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL PCR MICROPLATE FOR ROCHE 480 LIGHT CYCLER, WHITE W/SEALING FILM
PCR-96-LC480-W	CORNING	10/pk	EUR 293
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL PCR MICROPLATE FOR ROCHE 480 LIGHT CYCLER, WHITE (NO SEALING FILM)
PCR-96-LC480-W-NF	CORNING	10/pk	EUR 199
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

96 WELL BARCODED H1-H12, CLEAR LOW PROFILE PCR MICROPLATE FOR ABI, 0,1ML
PCR-96-LP-AB-C-PBC	CORNING	25/pk	EUR 421
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

MICROPLATE, DEEP WELL, 96 WELL, POLYPROPYLENE, 2.0 ML, CLEAR, SQUARE WELLS, NONSTERILE, BULK
P-2ML-SQ-C	CORNING	5/pk	EUR 107
Description: Deep Well/Assay Plates - Axygen; Deep-well plates - Axygen

MICROPLATE, DEEP WELL, 96 WELL, POLYPROPYLENE, 2.0 ML, CLEAR, SQUARE WELLS, STERILE, BULK
P-2ML-SQ-C-S	CORNING	25/pk	EUR 144
Description: Deep Well/Assay Plates - Axygen; Deep-well plates - Axygen

MICROPLATE, 96 WELL, POLYPROPYLENE, BLACK/CLEAR FLAT BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
9520	CORNING	25/pk	EUR 970
Description: Storage Barcodes; Barcoded Storage - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, BLACK/CLEAR FLAT BOTTOM, LAMININ-COATED, WITH LID, STERILE, BULK
7318A	CORNING	10/pk	EUR 1524
Description: Assay; Coated 96 Well Plt

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, FLAT BOTTOM, HIGH BINDING, NO LID, NONSTERILE, INDIVIDUALLY PACKAGED
3590	CORNING	1/pk	EUR 222
Description: Assay; EIA/RIA - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, FLAT BOTTOM, MEDIUM BINDING, NO LID, NONSTERILE, INDIVIDUALLY PACKAGED
3591	CORNING	1/pk	EUR 130
Description: Assay; EIA/RIA - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, WHITE, FLAT BOTTOM, NON BINDING SURFACE, NO LID, NONSTERILE, BULK
3600	CORNING	25/pk	EUR 780
Description: Assay; NBS - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, BLACK/CLEAR FLAT BOTTOM, HIGH BINDING, NO LID, NONSTERILE, BULK
3601	CORNING	25/pk	EUR 610
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, WHITE, ROUND BOTTOM, NON BINDING SURFACE, NO LID, NONSTERILE, BULK
3605	CORNING	25/pk	EUR 644
Description: Assay; NBS - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, BLACK/CLEAR FLAT BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
3631	CORNING	25/pk	EUR 626
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, WHITE/CLEAR FLAT BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
3632	CORNING	25/pk	EUR 664
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, FLAT BOTTOM, NON BINDING SURFACE, NO LID, NONSTERILE, BULK
3641	CORNING	25/pk	EUR 472
Description: Assay; NBS - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, BLACK, FLAT BOTTOM, NON BINDING SURFACE, NO LID, NONSTERILE, BULK
3650	CORNING	25/pk	EUR 716
Description: Assay; NBS - 96 Well

CORNING® MULTICOATED MICROPLATE, 96-WELL, BLACK CLEAR-BOTTOM, NON-STERILE, WITH LID, BULK
3823	CORNING	10/pk	EUR 769
Description: Assay; Coated 96 Well Plt

CORNING® MULTICOATED MICROPLATE, 1536-WELL, BLACK CLEAR-BOTTOM, NON-STERILE, WIT LID, BULK
3829	CORNING	10/pk	EUR 1631
Description: Assay; Coated 1536 Well Plt

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, V-BOTTOM, NOT TREATED, NO LID, STERILE, INDIVIDUALLY PACKAGED
3896	CORNING	1/pk	EUR 175
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, V-BOTTOM, NOT TREATED, NO LID, NONSTERILE, GENERIC BC
3897BC	CORNING	25/pk	EUR 280
Description: Assay; Barcoded - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, WHITE/CLEAR FLAT BOTTOM, TC-TREATED, WITH LID, STERILE, BULK
3903	CORNING	20/pk	EUR 743
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, BLACK/CLEAR FLAT BOTTOM, TC-TREATED, WITH LID, STERILE, BULK
3904	CORNING	20/pk	EUR 648
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, WHITE, FLAT BOTTOM, NON BINDING SURFACE, NO LID, NONSTERILE, BULK
3990	CORNING	5/pk	EUR 220
Description: Assay; NBS - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, BLACK, FLAT BOTTOM, NON BINDING SURFACE, NO LID, NONSTERILE, BULK
3991	CORNING	5/pk	EUR 204
Description: Assay; NBS - 96 Well

MICROPLATE, 96 WELL, POLYSTYRENE, CLEAR, ROUND BOTTOM, NOT TREATED, NO LID, STERILE, INDIVIDUALLY PACKAGED
3367	CORNING	1/pk	EUR 139
Description: Assay; General Assay - 96 Well

MICROPLATE, 1536 WELL, COC, WHITE, TC TREATED, NO LID, STERILE, BULK,BC SHORT SIDES
4370	CORNING	10/pk	EUR 790
Description: Assay; Barcoded - 1536 Well

MICROPLATE, 1536 WELL, COC, BLACK, NOT TREATED, NO LID, NONSTERILE, BULK,BC SHORT SIDES
4371	CORNING	10/pk	EUR 691
Description: Assay; Barcoded - 1536 Well

MICROPLATE, 1536 WELL, COC, WHITE, NOT TREATED, NO LID, NONSTERILE, BULK,BC SHORT SIDES
4372	CORNING	10/pk	EUR 691
Description: Assay; Barcoded - 1536 Well

MICROPLATE, 1536 WELL, COC, BLACK CLEAR BOTTOM, POLY-D-LYSINE, NO LID, NONSTERILE, BULK
4564	CORNING	20/pk	EUR 3671
Description: Assay; Barcoded - 1536 Well

MICROPLATE, 1536 WELL, COC, BLACK,CORNING® CELLBIND® SURFACE, NO LID, STERILE, BULK
4568	CORNING	10/pk	EUR 981
Description: Assay; Barcoded - 1536 Well

MICROPLATE, 1536 WELL, COC, WHITE, CORNING® CELLBIND® SURFACE, NO LID, STERILE, BULK
4573	CORNING	10/pk	EUR 1031
Description: Assay; Barcoded - 1536 Well

CORNING® MULTICOATED MICROPLATE, 384-WELL, BLACK CLEAR-BOTTOM, NON-STERILE, WITH LID, BULK
4589	CORNING	1/pk	EUR 833
Description: Assay; Coated 384 Well Plt

MICROPLATE, 1536 WELL, COC, BLACK , TC TREATED, NO LID, STERILE, BULK,BC SHORT SIDES
4705	CORNING	10/pk	EUR 790
Description: Assay; Barcoded - 1536 Well

MICROPLATE, 96 WELL, POLYVINYL CHLORIDE, CLEAR, V-BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
2897	CORNING	25/pk	EUR 185
Description: Assay; General Assay - 96 Well

Cell Meter™ Cell Viability Assay Kit NIR Fluorescence Optimized for Fluorescence Microplate Reader
22787	AAT Bioquest	200 Tests	EUR 219
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

Cell Meter™ Phosphatidylserine Apoptosis Assay Kit Deep Red Fluorescence Optimized for Microplate Readers
22793	AAT Bioquest	100 Tests	EUR 219
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

Cell Meter™ JC-10 Mitochondrion Membrane Potential Assay Kit Optimized for Microplate Assays
22800	AAT Bioquest	500 Tests	EUR 306
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

Cell Meter™ Mitochondrion Membrane Potential Assay Kit Orange Fluorescence Optimized for Microplate Reader
22805	AAT Bioquest	500 Tests	EUR 219
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

Cell Meter™ Mitochondrion Membrane Potential Assay Kit Red Fluorescence Optimized for Microplate Reader
22807	AAT Bioquest	500 tests	EUR 219
R-phrase: R20, R21, R22 H-Phrase: H303, H313, H333 Symbol for dangerous compounds: Xn UNSPEC Code: 12352200

MICROPLATE, 96 WELL, POLYVINYL CHLORIDE, CLEAR, FLAT BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
2595	CORNING	25/pk	EUR 172
Description: Assay; General Assay - 96 Well

MICROPLATE, 96 WELL, POLYVINYL CHLORIDE, CLEAR, ROUND BOTTOM, NOT TREATED, NO LID, NONSTERILE, BULK
2797	CORNING	25/pk	EUR 172
Description: Assay; General Assay - 96 Well

384 WELL PCR MICROPLATE. COMPATIBLE WITH ABI 3730 AND 3100 AND MJ THERMOCYCLERS. CLEAR
PCR-384M2-C	CORNING	10/pk	EUR 183
Description: PCR Plates & Tubes; A354 PCR Plate-Axygen

ELISA Microplate Shaker & incubator (holds 2, 96 well plate; room temp-40oC; 575-1500 rpm shaking; digital timer, compact)
MPS-800	Alpha Diagnostics	1	EUR 2425

FALCON® 96 SQUARE WELL FLAT BOTTOM MICROPLATE, WITH LID, NONSTERILE, 5/PACK, 5/CASE
353928	CORNING	5/pk	EUR 169
Description: Permeable Support - DL; HTS Transwells - DL

CORNING® BIOCOAT™ POLY-D-LYSINE 1536 WELL BLACK FLAT BOTTOM MICROPLATE, 5/CASE
354022	CORNING	5/pk	EUR 303
Description: Advanced Cells - DL; Assay 1536 well

MICROPLATE, 96 WELL, POLYSTYRENE, BLACK/CLEAR FLAT BOTTOM, TC-TREATED, WITH LID, STERILE, INDIVIDUALLY PACKAGED
3603	CORNING	1/pk	EUR 337
Description: Assay; General Assay - 96 Well

The biomarker diagnostics discipline has been revolutionized by next-generation sequencing (NGS), which supplies a complete overview of the genomic profile of a tumor. Many preanalytic variables can affect the accuracy and reliability of NGS outcomes. Standardization of preanalytic variables is, nevertheless, difficult by the plethora of specimen acquisition and processing strategies. Variables throughout the tissue journey, together with specimen acquisition, specimen fixation, and sectioning, in addition to postfixation processing, reminiscent of nucleic acid extraction, library preparation, and choice of sequencing strategies, are vital for the reliability of NGS analysis; thus, standardization can be useful.

Quality control and quantification in IG/TR next-generation sequencing marker identification: protocols and bioinformatic functionalities by EuroClonality-NGS.

Assessment of clonality, marker identification and measurement of minimal residual illness (MRD) of immunoglobulin (IG) and T cell receptor (TR) gene rearrangements in lymphoid neoplasms utilizing next-generation sequencing (NGS) is presently below intensive improvement to be used in scientific diagnostics. So far, nevertheless, there’s a lack of appropriate high quality control (QC) choices with regard to standardisation and high quality metrics to make sure strong scientific software of such approaches. The EuroClonality-NGS Working Group has due to this fact established two varieties of QCs to accompany the NGS-based IG/TR assays.

First, a central polytarget QC (cPT-QC) is used to watch the primer efficiency of every of the EuroClonality multiplex NGS assays; second, a standardised human cell line-based DNA control is spiked into every affected person DNA pattern to work as a central in-tube QC and calibrator for MRD quantification (cIT-QC). Having built-in these two reference requirements in the ARResT/Interrogate bioinformatic platform, EuroClonality-NGS gives a whole protocol for standardised IG/TR gene rearrangement evaluation by NGS with excessive reproducibility, accuracy and precision for legitimate marker identification and quantification in diagnostics of lymphoid malignancies.

Amplicon-based next-generation sequencing (NGS) of immunoglobulin (IG) and T-cell receptor (TR) gene rearrangements for clonality evaluation, marker identification and quantification of minimal residual illness (MRD) in lymphoid neoplasms has been the main target of intense analysis, improvement and software. However, standardization and validation in a scientifically managed multicentre setting remains to be missing.

Therefore, IG/TR assay improvement and design, together with bioinformatics, was carried out throughout the EuroClonality-NGS working group and validated for MRD marker identification in acute lymphoblastic leukaemia (ALL). Five EuroMRD ALL reference laboratories carried out IG/TR NGS in 50 diagnostic ALL samples, and in contrast outcomes with these generated by way of routine IG/TR Sanger sequencing. A central polytarget high quality control (cPT-QC) was used to watch primer efficiency, and a central in-tube high quality control (cIT-QC) was spiked into every pattern as a library-specific high quality control and calibrator.

NGS recognized 259 (common 5.2/pattern, vary 0-14) clonal sequences vs. Sanger-sequencing 248 (common 5.0/pattern, vary 0-14). NGS primers lined doable IG/TR rearrangement varieties extra utterly in contrast with native multiplex PCR units and enabled sequencing of bi-allelic rearrangements and weak PCR merchandise. The cPT-QC confirmed excessive reproducibility throughout all laboratories. These validated and reproducible quality-controlled EuroClonality-NGS assays can be utilized for standardized NGS-based identification of IG/TR markers in lymphoid malignancies.

New Challenges in Tumor Mutation Heterogeneity in Advanced Ovarian Cancer by a Targeted Next-Generation Sequencing (NGS) Approach.

Next-generation sequencing (NGS) expertise has superior information of the genomic panorama of ovarian most cancers, resulting in an revolutionary molecular classification of the illness. However, affected person survival and response to platinum-based remedies are nonetheless not predictable based mostly on the tumor genetic profile. This retrospective research characterised the repertoire of somatic mutations in superior ovarian most cancers to establish tumor genetic markers predictive of platinum chemo-resistance and prognosis. In specific, we recognized a poor prognostic signature in sufferers with HGSOC harboring concurrent mutations in two driver actionable genes of the panel.

Using focused NGS, 79 main superior (III-IV stage, tumor grade G2-3) ovarian most cancers tumors, together with 64 high-grade serous ovarian cancers (HGSOCs), had been screened with a 26 cancer-genes panel. Patients, enrolled between 1995 and 2011, underwent main debulking surgical procedure (PDS) with optimum residual illness (RD < 1 cm) and platinum-based chemotherapy as first-line remedy. We discovered a heterogeneous mutational panorama in some unusual ovarian histotypes and in HGSOC tumor samples with relevance in predicting platinum sensitivity.

The tumor heterogeneity described, sheds mild on the translational potential of focused NGS strategy for the identification of subgroups of sufferers with distinct therapeutic vulnerabilities, which are modulated by the precise mutational profile expressed by the ovarian tumor. Given the big selection of mutations related to hematologic malignancies a DNA/RNA-based NGS panel can present a simpler and economical strategy to complete testing of sufferers as an preliminary, tier-1 display.

Next-generation sequencing of immunoglobulin gene rearrangements for clonality evaluation: a technical feasibility research by EuroClonality-NGS.

One of the hallmarks of B lymphoid malignancies is a B cell clone characterised by a novel footprint of clonal immunoglobulin (IG) gene rearrangements that serves as a diagnostic marker for clonality evaluation. The EuroClonality/BIOMED-2 assay is presently the gold normal for analyzing IG heavy chain (IGH) and κ mild chain (IGK) gene rearrangements of suspected B cell lymphomas. Here, the EuroClonality-NGS Working Group presents a multicentre technical feasibility research of a novel strategy involving next-generation sequencing (NGS) of IGH and IGK loci rearrangements that’s extremely appropriate for detecting IG gene rearrangements in frozen and formalin-fixed paraffin-embedded tissue specimens.

By using gene-specific primers for IGH and IGK amplifying smaller amplicon sizes in mixture with deep sequencing expertise, this NGS-based IG clonality evaluation confirmed strong efficiency, even in DNA samples of suboptimal DNA integrity, and a excessive scientific sensitivity for the detection of clonal rearrangements. Bioinformatics analyses of the high-throughput sequencing information with ARResT/Interrogate, a platform developed throughout the EuroClonality-NGS Working Group, allowed correct identification of clonotypes in each polyclonal cell populations and monoclonal lymphoproliferative problems.

Universal DNA Marker (100 bp ~ 10,000 bp)
W2583-50	101Bio	NULL	EUR 0

Universal DNA Marker (100 bp ~ 10,000 bp)
W2583-500	101Bio	NULL	EUR 0

Methylamp Universal Methylated DNA Kit
P-1011	EpiGentek	20 Modifications	EUR 570.55
Description: kits suitable for this type of research

Methylamp Universal Methylated DNA Preparation Kit
P-1019	EpiGentek	40 µg	EUR 347.25
Description: The best epigenetics products

100 BP DNA LADDER, 500UL PER KIT
M-DNA-100BP	CORNING	1/pk	EUR 73
Description: Bioscience Mol Bio; DNA Ladder

1 KB DNA LADDER, 500UL PER KIT
M-DNA-1KB	CORNING	1/pk	EUR 70
Description: Bioscience Mol Bio; DNA Ladder

VAHTS Universal DNA Library Prep Kit for MGI
NDM607-01	Vazyme	24 rxn	EUR 733

VAHTS Universal DNA Library Prep Kit for MGI
NDM607-02	Vazyme	96 rxn	EUR 2136

100bp DNA Marker
D1100-050	GenDepot	50㎍	EUR 165

100bp DNA Marker
D1100-250	GenDepot	5X50㎍	EUR 550

1Kb DNA Marker
D1101-050	GenDepot	50㎍	EUR 131

1Kb DNA Marker
D1101-250	GenDepot	5X50㎍	EUR 300

2K DNA Marker
20-abx098045	Abbexa	EUR 258.00 EUR 189.00	2.5 ml 500 ul
Shipped within 5-10 working days.

5K DNA Marker
20-abx098048	Abbexa	EUR 258.00 EUR 189.00	2.5 ml 500 ul
Shipped within 5-10 working days.

15K DNA Marker
20-abx098049	Abbexa	EUR 272.00 EUR 189.00	2.5 ml 500 ul
Shipped within 5-10 working days.

1Kb DNA Marker
20-abx098050	Abbexa	EUR 258.00 EUR 189.00	2.5 ml 500 ul
Shipped within 5-10 working days.

100bp DNA Marker
20-abx098052	Abbexa	EUR 272.00 EUR 189.00	2.5 ml 500 ul
Shipped within 5-10 working days.

DL5000 DNA Marker
MD102-01	Vazyme	250 μl	EUR 107

DL5000 DNA Marker
MD102-02	Vazyme	500 μl	EUR 113

DL15000 DNA Marker
MD103-01	Vazyme	250 μl	EUR 109

DL15000 DNA Marker
MD103-02	Vazyme	500 μl	EUR 115

VAHTS Universal DNA Library Prep Kit for Illumina V3
ND607-01	Vazyme	24 rxn	EUR 441

VAHTS Universal DNA Library Prep Kit for Illumina V3
ND607-02	Vazyme	96 rxn	EUR 1405

VAHTS Universal Pro DNA Library Prep Kit for Illumina
ND608-01	Vazyme	24 rxn	EUR 465

VAHTS Universal Pro DNA Library Prep Kit for Illumina
ND608-02	Vazyme	96 rxn	EUR 1549

VAHTS Universal Plus DNA Library Prep Kit for Illumina
ND617-01	Vazyme	24 rxn	EUR 492

VAHTS Universal Plus DNA Library Prep Kit for Illumina
ND617-02	Vazyme	96 rxn	EUR 1605

VAHTS Universal DNA Library Prep Kit for Ion Torrent
ND701-01	Vazyme	24 rxn	EUR 733

VAHTS Universal DNA Library Prep Kit for Ion Torrent
ND701-02	Vazyme	96 rxn	EUR 2136

VAHTS Universal Pro DNA Library Prep Kit for MGI
NDM608-01	Vazyme	24 rxn	EUR 756

VAHTS Universal Pro DNA Library Prep Kit for MGI
NDM608-02	Vazyme	96 rxn	EUR 2284

VAHTS Universal Plus DNA Library Prep Kit for MGI
NDM617-01	Vazyme	24 rxn	EUR 824

VAHTS Universal Plus DNA Library Prep Kit for MGI
NDM617-02	Vazyme	96 rxn	EUR 2408

UNIVERSAL PLATFORM
480144	CORNING	1/pk	EUR 269
Description: Lab Equipment; Constant Temperature Equipment

1Kb Plus DNA Marker
20-abx098051	Abbexa	EUR 300.00 EUR 203.00	2.5 ml 500 ul
Shipped within 5-10 working days.

DL2000 Plus DNA Marker
MD101-01	Vazyme	250 μl	EUR 107

DL2000 Plus DNA Marker
MD101-02	Vazyme	500 μl	EUR 113

Linear Kinetoplast DNA Marker
TG2018-1	TopoGen	10 ug	EUR 179

Decatenated Kinetoplast DNA Marker
TG2020-1	TopoGen	10 ug	EUR 190

Relaxed pRYG DNA Marker
TG2025-1	TopoGen	10 ug	EUR 268

Linear pRYG DNA Marker
TG2028-1	TopoGen	10 ug	EUR 179

1 Kb Ladder DNA Marker
FYD001-500UL	Yeastern Biotech	20 µg/ 500 µl	Ask for price

100 bp Ladder DNA Marker
FYD002-500UL	Yeastern Biotech	30 µg/ 500 µl	Ask for price

50 bp Ladder DNA Marker
FYD004-500UL	Yeastern Biotech	32.5 µg/ 500 µl	Ask for price

Universal Coating Solution
AC002	Neuromics	20 ml	EUR 297

Universal Detachment Solution
AD002	Neuromics	100 ml	EUR 148

Universal Spring Platform
H1000-P-SP	BenchMark	1 PC	EUR 323.39
To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Universal Neutralization Buffer
NB001	Neuromics	100 ml	EUR 135

UNIVERSAL BEER AGAR
U21-100-10kg	Alphabiosciences	10 kg	EUR 1524

UNIVERSAL BEER AGAR
U21-100-2kg	Alphabiosciences	2kg	EUR 370

UNIVERSAL BEER AGAR
U21-100-500g	Alphabiosciences	500 g	EUR 137

UNIVERSAL PREENRICHMENT BROTH
U21-101-10kg	Alphabiosciences	10 kg	EUR 749

UNIVERSAL PREENRICHMENT BROTH
U21-101-2Kg	Alphabiosciences	2 Kg	EUR 202

UNIVERSAL PREENRICHMENT BROTH
U21-101-500g	Alphabiosciences	500 g	EUR 91

Universal qPCR Mixture
QPCR1000-UNIV	Bio Basic	4X1.25ml	EUR 276.2
Product category: PCR Related/PCR Premix (qPCR)/qPCR Premix + Taq

VAHTS Universal DNA Library Prep Kit for Illumina V3 (PCR-Free)
ND607-03	Vazyme	24 rxn	EUR 429

VAHTS Universal DNA Library Prep Kit for Illumina V3 (PCR-Free)
ND607-04	Vazyme	96 rxn	EUR 1354

Image Green? 100 bp DNA Marker
M1155-500	Biovision		EUR 294

Image Green? 1 kb DNA Marker
M1156-500	Biovision		EUR 294

50-500bp Low Range DNA Marker
GM305	Bio Basic	200loading, 200prep	EUR 114.82
Product category: Electrophoresis Related/Ladders - DNA/50-500 bp

500-10000bp DNA Marker, Original Form
M101O-1	Bio Basic	100loading, 100prep	EUR 91.76
Product category: Electrophoresis Related/Ladders - DNA/500-10000 bp

500-10000bp DNA Marker, Original Form
M101O-2	Bio Basic	5x100loading, 500prep	EUR 219.65
Product category: Electrophoresis Related/Ladders - DNA/500-10000 bp

100-1500bp DNA Marker, Original Form
M102O-1	Bio Basic	100loading, 100prep	EUR 90.02
Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Original Form
M102O-2	Bio Basic	5x100loading, 500prep	EUR 215.3
Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Original Form
M107O-1	Bio Basic	100loading, 100prep	EUR 91.76
Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Original Form
M107O-2	Bio Basic	5x100loading, 500prep	EUR 219.65
Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

2K Plus DNA Marker (8 linear double-stranded DNA bands)
20-abx098046	Abbexa	EUR 258.00 EUR 189.00	2.5 ml 500 ul
Shipped within 5-10 working days.

2K Plus DNA Marker (9 linear double-stranded DNA bands)
20-abx098047	Abbexa	EUR 258.00 EUR 189.00	2.5 ml 500 ul
Shipped within 5-10 working days.

100bp Plus DNA Marker (12 linear double-stranded DNA bands)
20-abx098053	Abbexa	EUR 272.00 EUR 189.00	2.5 ml 500 ul
Shipped within 5-10 working days.

100bp Plus DNA Marker (14 linear double-stranded DNA bands)
20-abx098054	Abbexa	EUR 300.00 EUR 203.00	2.5 ml 500 ul
Shipped within 5-10 working days.

Universal Casein Diluent/Blocker
85R-108	Fitzgerald	250 ml	EUR 230
Description: Ready-to-use biotin free reagent applicable for blocking ELISA plates

5min Universal Ligation Mix
C311-01	Vazyme	50 rxn	EUR 214

5min Universal Ligation Mix
C311-02	Vazyme	100 rxn	EUR 283

PCR plate-foil universal
A28216	GeneOn	1x100 pcs	EUR 94

PCR plate-foil universal
A28216L	GeneOn	5x100 pcs	EUR 310

Universal Full Growth Medium
TM001	Neuromics	500 ml	EUR 336

Universal Protein Precipitating Reagent
BSP012	Bio Basic	100preps	EUR 81.32
Product category: Molecular Biology Kits/Protein - Purification/Precipitation

Tumour Marker MUC1 (S1.1) , DNA Aptamer, Biotinylated
AD-152-B	Alpha Diagnostics	Custom	Ask for price

Tumour Marker MUC1 (S1.1) , DNA Aptamer, unlabeled
AD-152-U	Alpha Diagnostics	Custom	Ask for price

100-1200bp DNA Marker, Ready-to-use
GM333	Bio Basic	50loading, 50prep	EUR 67.4
Product category: Electrophoresis Related/Ladders - DNA/100-1200 bp

100-1200bp DNA Marker, Ready-to-use
GM334	Bio Basic	5x50loading, 250prep	EUR 128.3
Product category: Electrophoresis Related/Ladders - DNA/100-1200 bp

100-2000bp DNA Marker, Ready-to-use
GM335	Bio Basic	50loading, 50prep	EUR 67.4
Product category: Electrophoresis Related/Ladders - DNA/100-2000 bp

100-2000bp DNA Marker, Ready-to-use
GM336	Bio Basic	5x50loading, 250prep	EUR 128.3
Product category: Electrophoresis Related/Ladders - DNA/100-2000 bp

200-1500bp DNA Marker, Ready-to-use
GM337	Bio Basic	50loading, 50prep	EUR 67.4
Product category: Electrophoresis Related/Ladders - DNA/200-1500 bp

200-1500bp DNA Marker, Ready-to-use
GM338	Bio Basic	5x50loading, 250prep	EUR 128.3
Product category: Electrophoresis Related/Ladders - DNA/200-1500 bp

200-2000bp DNA Marker, Ready-to-use
GM339	Bio Basic	50loading, 50prep	EUR 67.4
Product category: Electrophoresis Related/Ladders - DNA/200-2000 bp

200-2000bp DNA Marker, Ready-to-use
GM340	Bio Basic	5x50loading, 250prep	EUR 128.3
Product category: Electrophoresis Related/Ladders - DNA/200-2000 bp

300-2500bp DNA Marker, Ready-to-use
GM341	Bio Basic	50loading, 50prep	EUR 67.4
Product category: Electrophoresis Related/Ladders - DNA/300-2500 bp

300-2500bp DNA Marker, Ready-to-use
GM342	Bio Basic	5x50loading, 250prep	EUR 128.3
Product category: Electrophoresis Related/Ladders - DNA/300-2500 bp

100-1000bp DNA Marker, Ready-to-use
GM343	Bio Basic	50loading, 50prep	EUR 80.45
Product category: Electrophoresis Related/Ladders - DNA/100-1000 bp

100-1000bp DNA Marker, Ready-to-use
GM345	Bio Basic	50loading, 50prep	EUR 84.8
Product category: Electrophoresis Related/Ladders - DNA/100-1000 bp

500-10000bp DNA Marker, Ready-to-use
M101R-1	Bio Basic	100loading, 100prep	EUR 91.76
Product category: Electrophoresis Related/Ladders - DNA/500-10000 bp

500-10000bp DNA Marker, Ready-to-use
M101R-2	Bio Basic	5x100loading, 500prep	EUR 219.65
Product category: Electrophoresis Related/Ladders - DNA/500-10000 bp

100-1500bp DNA Marker, Ready-to-use
M102R-1	Bio Basic	100loading, 100prep	EUR 90.02
Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Ready-to-use
M102R-2	Bio Basic	5x100loading, 500prep	EUR 215.3
Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

Lambda DNA/HindIII Marker, Ready-to-use
M104R-1	Bio Basic	100loading, 100prep	EUR 65.66
Product category: Electrophoresis Related/Ladders - DNA/Lambda DNA/HindIII

Lambda DNA/HindIII Marker, Ready-to-use
M104R-2	Bio Basic	5x100loading, 500prep	EUR 124.82
Product category: Electrophoresis Related/Ladders - DNA/Lambda DNA/HindIII

100-1500bp DNA Marker, Ready-to-use
M107R-1	Bio Basic	100loading, 100prep	EUR 91.76
Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Ready-to-use
M107R-2	Bio Basic	5x100loading, 500prep	EUR 219.65
Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

50-1500bp DNA Marker, Ready-to-use
M109-A	Bio Basic	100loading, 100prep	EUR 91.76
Product category: Electrophoresis Related/Ladders - DNA/50-1500 bp

50-1500bp DNA Marker, Ready-to-use
M109-B	Bio Basic	5x100loading, 500prep	EUR 219.65
Product category: Electrophoresis Related/Ladders - DNA/50-1500 bp

100-1500bp DNA Marker, Ready-to-use
SGM01	Bio Basic	50loading, 50prep	EUR 67.4
Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

100-1500bp DNA Marker, Ready-to-use
SGM02	Bio Basic	5x50loading, 250prep	EUR 128.3
Product category: Electrophoresis Related/Ladders - DNA/100-1500 bp

UNIVERSAL LINEAR 4 PLACE STAND
AP-USD4	CORNING	1/pk	EUR 70
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Universal IHC Diluent/Blocker/Stabilizer
85R-1021	Fitzgerald	1 liter	EUR 692
Description: Universal Diluent/Blocker/Stabilizer for use in IHC

HotTaq Probe qPCR Universal Mix
BT11004	Bioatlas	250rxn	EUR 123
Description: High quality HotTaq polymerase for different PCR variations and downstream applications.

HotTaq EvaGreen qPCR Universal Mix
BT11104	Bioatlas	250rxn	EUR 138
Description: High quality HotTaq polymerase for different PCR variations and downstream applications.

VAHTS Universal Plus Fragmentation Module
N209-01	Vazyme	24 rxn	EUR 376

VAHTS Universal Plus Fragmentation Module
N209-02	Vazyme	96 rxn	EUR 1022

Universal 3' miRNA Reverse Primer
MPH00000	ABM	150 ul / 10 uM	EUR 70

100UL UNIVERSAL FIT FILTER TIPS
TF-100	CORNING	1000/pk	EUR 418
Description: Filter Tip; Filter Tips Pipette - Axygen

1000UL UNIVERSAL FIT FILTER TIPS
TF-1000	CORNING	1000/pk	EUR 232
Description: Filter Tip; Filter Tips Pipette - Axygen

200UL UNIVERSAL FIT FILTER TIPS
TF-200	CORNING	1000/pk	EUR 418
Description: Filter Tip; Filter Tips Pipette - Axygen

300UL UNIVERSAL FIT FILTER TIPS
TF-350	CORNING	1000/pk	EUR 418
Description: Filter Tip; Filter Tips Pipette - Axygen

50UL UNIVERSAL FIT FILTER TIPS
TF-50	CORNING	1000/pk	EUR 418
Description: Filter Tip; Filter Tips Pipette - Axygen

100bp DNA Marker Plus-50, Ready-to-use
D1103-050	GenDepot	500 ul	EUR 151

100bp DNA Marker Plus-50, Ready-to-use
D1103-100	GenDepot	2x500 ul	EUR 192

100bp PCR Ranger DNA Marker, 100bp-To-3Kb
D1108-100	GenDepot	1ml	EUR 220

100bp PCR Ranger DNA Marker, 100bp-To-3Kb
D1108-200	GenDepot	2x1ml	EUR 309

1Kb PCR Ranger DNA Marker, 750bp-To-20Kb
D1109-100	GenDepot	1ml	EUR 188

1Kb PCR Ranger DNA Marker, 750bp-To-20Kb
D1109-400	GenDepot	4x1ml	EUR 388

Tumour Marker MUC1 (S1.1) , DNA Aptamer, FITC labeled
AD-152-F	Alpha Diagnostics	Custom	Ask for price

200-2000bp DNA Marker Plus, Ready-to-use
GM401	Bio Basic	50loading, 50prep	EUR 60.44
Product category: Electrophoresis Related/Ladders - DNA/200-2000 bp

100-5000bp DNA Marker Plus, Ready-to-use
SGM03	Bio Basic	50loading, 50prep	EUR 67.4
Product category: Electrophoresis Related/Ladders - DNA/100-5000 bp

STAT Universal Animal IHC KIT-small
329ANK-20	Innovex	Small Kit	EUR 717

STAT Universal Animal IHC KIT-large
329ANK-60	Innovex	Large Kit	EUR 1088

Universal TT epitope P2 (830-844)
5-02048	CHI Scientific	4 x 1mg	Ask for price

UNIVERSAL CAROUSEL RACK FOR SIX PIPETTES
4078	CORNING	1/pk	EUR 132
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Single Channel Pipettors

UNIVERSAL LINEAR RACK FOR SIX PIPETTES
4079	CORNING	1/pk	EUR 70
Description: Corning and Axygen Liquid Handling Equipment; Corning Lambda Plus Single Channel Pipettors

Dog Adult Tissues Protein lysate, Universal
DOUL-4568	Alpha Diagnostics	1 mg	EUR 524

UNIVERSAL STAND FOR FOUR PIPETTORS, RED
AP-USD4-P	CORNING	1/pk	EUR 69
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

UNIVERSAL STAND FOR SIX PIPETTORS, TRANSPARENT
AP-USD6	CORNING	1/pk	EUR 85
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Enhanced Universal IHC Diluent/Blocker/Stabilizer
85R-1021E	Fitzgerald	100 ml	EUR 187
Description: Enhanced Universal Diluent/Blocker/Stabilizer for use in IHC

Chicken Adult Tissues Protein lysate, Universal
CHUL-4567	Alpha Diagnostics	1 mg	EUR 524

Universal miRNA qPCR Primer (10 µM)
abx298006-200ul	Abbexa	200 ul	EUR 189
Shipped within 5-10 working days.

Universal Stress Protein F (uspF) Antibody
20-abx300670	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

Human Adult Tissues Protein lysate, Universal
HUUL-4565	Alpha Diagnostics	1 mg	EUR 524

ADPsensor? Universal Kinase Activity Assay Kit
K212-100	Biovision		EUR 582

Universal Protein Lysate: Human Normal Tissues
P4234565	Biochain	4x0.5 mg	EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Human Normal Tissues
P4234565-1	Biochain	2x0.5 mg	EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Mouse Normal Tissues
P4334566	Biochain	4x0.5 mg	EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Mouse Normal Tissues
P4334566-1	Biochain	2x0.5 mg	EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Rat Normal Tissues
P4434567	Biochain	4x0.5 mg	EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Rat Normal Tissues
P4434567-1	Biochain	2x0.5 mg	EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Monkey Normal Tissues
P4534565	Biochain	4x0.5 mg	EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Monkey Normal Tissues
P4534565-1	Biochain	2x0.5 mg	EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Dog Normal Tissues
P4734565	Biochain	4x0.5 mg	EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Dog Normal Tissues
P4734565-1	Biochain	2x0.5 mg	EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Chicken Normal Tissues
P4C34565	Biochain	4x0.5 mg	EUR 403
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

Universal Protein Lysate: Chicken Normal Tissues
P4C34565-1	Biochain	2x0.5 mg	EUR 285
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

UNIVERSAL POWER SUPPLY FOR AXYGEN MOTOPET
MOTO-SP-PWR	CORNING	1/pk	EUR 61
Description: Handheld Pipettor Repairs; Liquid Handling Device Repairs

Mouse Adult Tissues Protein lysate, Universal
MOUL-4566	Alpha Diagnostics	1 mg	EUR 524

Monkey Adult Tissues Protein lysate, Universal
MKUL-4569	Alpha Diagnostics	1 mg	EUR 524

Universal RNA from Human Normal Tissues
R4234565	Biochain	4x100 ug	EUR 628
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Human Normal Tissues
R4234565-1	Biochain	2x100 ug	EUR 390
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Mouse Normal Tissues
R4334566	Biochain	4x100 ug	EUR 530
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Mouse Normal Tissues
R4334566-1	Biochain	2x100 ug	EUR 311
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Rat Normal Tissues
R4434567	Biochain	4x100 ug	EUR 530
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Rat Normal Tissues
R4434567-1	Biochain	2x100 ug	EUR 311
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Monkey Normal Tissues
R4534565	Biochain	4x100 ug	EUR 628
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Monkey Normal Tissues
R4534565-1	Biochain	2x100 ug	EUR 390
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

Universal RNA from Dog Normal Tissues
R4734565	Biochain	4x100 ug	EUR 628
Description: Can be used for various studies in the realm of gene expression and regulation, both normal and pathological. It is an excellent control and suitable for educational purposes.

This multicentre feasibility research is a vital step in the direction of implementation of NGS-based clonality evaluation in scientific apply, which is able to ultimately enhance lymphoma diagnostics. The analysis of hematologic malignancies integrates a number of diagnostic and scientific disciplines. Historically, focused (single-analyte) genetic testing has been used as reflex to preliminary prescreening by different diagnostic modalities together with move cytometry, anatomic pathology, and scientific cytogenetics.

Isolation of Novel MAMP-like Activities and Identification of Cognate Pattern Recognition Receptors in Arabidopsis thaliana Using Next-Generation Sequencing (NGS)-Based Mapping.

Activation of pattern-triggered plant immunity requires recognition of microbe-derived molecular patterns (MAMPs) by plant-encoded sample recognition receptors (PRRs). Many plant PRRs are discovered in chosen plant genera solely. Transfer of single PRRs or of cassettes expressing a number of PRRs (PRR stacking) throughout plant genus boundaries provides the potential to spice up illness resistance by enhancing pathogen recognition options in economically necessary crop vegetation. The success of such an method is most depending on the provision of a big quantity of plant PRRs. Here, an environment friendly technique for the identification of novel PRRs in the mannequin plant Arabidopsis thaliana (hereafter, Arabidopsis for simplicity) is described.

This technique takes benefit of pure variation in microbial sample sensitivity amongst tons of of Arabidopsis accessions presently obtainable. Identification of pattern-sensitive in addition to pattern-insensitive accessions facilitates next-generation sequencing (NGS)-assisted mapping of PRRs. This method is probably relevant to the identification of PRRs that acknowledge patterns of any chemical nature. Following the completion of the Human Genome Project in 2003, analysis in oncology has progressively centered on the sequencing of most cancers genomes, with the purpose of higher understanding the genetic foundation of oncogenesis and figuring out actionable alterations.

The improvement of next-generation-sequencing (NGS) strategies, commercially obtainable since 2006, allowed for a cost- and time-effective sequencing of tumor DNA, resulting in a “genomic period” of most cancers analysis and therapy. NGS supplied a big step ahead in Personalized Medicine (PM) by enabling the detection of somatic driver mutations, resistance mechanisms, quantification of mutational burden, germline mutations which settled the muse of a brand new method in most cancers care. In this chapter we focus on the historical past, obtainable strategies and purposes of NGS in oncology, with a selected referral to the PM method and the rising function of the analysis discipline of pharmacogenomics.

Standardization of Sequencing Coverage Depth in NGS: Recommendation for Detection of Clonal and Subclonal Mutations in Cancer Diagnostics.

The inadequate standardization of diagnostic next-generation sequencing NGS) nonetheless limits its implementation in medical apply, with the proper detection of mutations at low variant allele frequencies( (VAF) dealing with explicit challenges. We handle right here the standardization of sequencing protection depth in order to reduce the chance of false constructive and false damaging outcomes, the latter being underestimated in medical NGS. There is presently no consensus on the minimal protection depth, and so every laboratory has to set its personal parameters. To help laboratories with the willpower of the minimal protection parameters, we offer right here a user-friendly protection calculator.

Using the sequencing error solely, we suggest a minimal depth of protection of 1,650 along with a threshold of not less than 30 mutated reads for a focused NGS mutation evaluation of ≥3% VAF, primarily based on the binomial chance distribution. Moreover, our calculator additionally permits including assay-specific errors occurring throughout DNA processing and library preparation, thus calculating with an general error of a selected NGS assay. The estimation of appropriate protection depth is advisable as a place to begin when assessing thresholds of NGS assay.

Our research additionally factors to the necessity for steerage concerning the minimal technical necessities, which primarily based on our expertise ought to embody the restrict of detection (LOD), general NGS assay error, enter, supply and high quality of DNA, protection depth, quantity of variant supporting reads, and whole quantity of goal reads masking variant area. Further research are wanted to outline the minimal technical necessities and its reporting in diagnostic NGS. So far, regardless of availability of NGS diagnostics at college institutes of pathology, solely few bladder most cancers samples have been sequenced.

Isolation of Novel MAMP-like Activities and Identification of Cognate Pattern Recognition Receptors in Arabidopsis thaliana Using Next-Generation Sequencing (NGS)-Based Mapping.

[Status of the availability and use of next generation sequencing (NGS) in bladder cancer-a questionnaire within the uropathology working group].

Technical development and availability of high-throughput evaluation has superior molecular subtyping of most cancers. Thus, new prospects for precision oncology have emerged.Therefore, we aimed to gather information concerning availability and use of subsequent technology sequencing (NGS) for urothelial most cancers throughout the uropathology working group of the German Society of Pathology.We collected information by questionnaires and moreover requested for sequencing outcomes of bladder cancers in the taking part establishments.

A complete of 13 university-affiliated institutes of pathology took half in the survey. All college institutes supply NGS-based molecular panel diagnostics and present panels masking between 15 and 170 genes. Altogether, solely 20 bladder cancers had been sequenced in routine diagnostics and for 10 cancers potential focused therapy choices had been obtainable.Based on present information from the molecular subtyping of bladder cancers, we suggest a step-by-step protocol with primary immunohistochemistry evaluation and subsequent subtype-dependent analyses, e.g., alterations of the fibroblast development issue receptors (FGFR) or complete gene panel analyses.

WD Repeat And SOCS Box-Containing Protein 1 (WSB1) Antibody
20-abx126795	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

WD Repeat And SOCS Box-Containing Protein 1 (WSB1) Antibody
abx239526-100ug	Abbexa	100 ug	EUR 551
Shipped within 5-12 working days.

WD Repeat And SOCS Box-Containing Protein 1 (WSB1) Antibody
20-abx338867	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

WD Repeat And SOCS Box-Containing Protein 1 (WSB1) Antibody (HRP)
20-abx338305	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

WD Repeat And SOCS Box-Containing Protein 1 (WSB1) Antibody (FITC)
20-abx338306	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

WD Repeat And SOCS Box-Containing Protein 1 (WSB1) Antibody (Biotin)
20-abx338307	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

WD Repeat And SOCS Box-Containing Protein 2 (WSB2) Antibody
20-abx124709	Abbexa	EUR 411.00 EUR 592.00	100 ul 200 ul
Shipped within 5-10 working days.

WD Repeat And SOCS Box-Containing Protein 2 (WSB2) Antibody
abx033017-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

WD Repeat And SOCS Box-Containing Protein 2 (WSB2) Antibody
abx033017-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

WD Repeat And SOCS Box-Containing Protein 2 (WSB2) Antibody
abx239527-100ug	Abbexa	100 ug	EUR 509
Shipped within 5-12 working days.

Wd Repeat And Socs Box-Containing 2 (WSB1) Antibody
20-abx116647	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

Wd Repeat And Socs Box-Containing 2 (WSB2) Antibody
20-abx116648	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

WD Repeat, SAM And U-Box Domain-Containing Protein 1 (WDSUB1) Antibody
abx034117-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

WD Repeat, SAM And U-Box Domain-Containing Protein 1 (WDSUB1) Antibody
abx034117-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing Protein 7 (FBXW7) Antibody
20-abx212397	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing Protein 7 (FBXW7) Antibody
20-abx212888	Abbexa	EUR 411.00 EUR 300.00	100 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing Protein 7 (FBXW7) Antibody
20-abx128045	Abbexa	EUR 425.00 EUR 133.00 EUR 1205.00 EUR 578.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug
Shipped within 5-7 working days.

F-Box And WD Repeat Domain Containing Protein 7 (FBXW7) Antibody
20-abx129356	Abbexa	EUR 439.00 EUR 133.00 EUR 1233.00 EUR 592.00 EUR 328.00	100 ug 10 ug 1 mg 200 ug 50 ug
Shipped within 5-7 working days.

F-Box And WD Repeat Domain Containing 11 (FBXW11) Antibody
20-abx007164	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 12 (FBXW12) Antibody
abx025658-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 12 (FBXW12) Antibody
abx025658-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 11 (FBXW11) Antibody
abx026152-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 11 (FBXW11) Antibody
abx026152-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 4 (FBXW4) Antibody
20-abx005895	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 7 (FBXW7) Antibody
20-abx006803	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 11 (FBXW11) Antibody
20-abx112491	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 2 (FBXW2) Antibody
20-abx112492	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 4 (FBXW4) Antibody
20-abx112493	Abbexa	EUR 732.00 EUR 398.00	150 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 5 (FBXW5) Antibody
20-abx123928	Abbexa	EUR 411.00 EUR 592.00 EUR 182.00 EUR 314.00	100 ul 200 ul 20 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 7 (FBXW7) Antibody
20-abx124024	Abbexa	EUR 411.00 EUR 592.00	100 ul 200 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 11 (FBXW11) Antibody
abx036648-100ug	Abbexa	100 ug	EUR 391
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 11 (FBXW11) Antibody
abx036649-100ug	Abbexa	100 ug	EUR 391
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 12 (FBXW12) Antibody
abx037103-100ug	Abbexa	100 ug	EUR 391
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 4 (FBXW4) Antibody
abx037921-100ug	Abbexa	100 ug	EUR 391
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 7 (FBXW7) Antibody
abx145824-100ug	Abbexa	100 ug	EUR 391
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 2 (FBXW2) Antibody
abx146055-100ug	Abbexa	100 ug	EUR 391
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 5 (FBXW5) Antibody
abx031051-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 5 (FBXW5) Antibody
abx031051-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 4 (FBXW4) Antibody
abx031451-400ul	Abbexa	400 ul	EUR 523
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 4 (FBXW4) Antibody
abx031451-80l	Abbexa	80 µl	EUR 286
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 11 (FBXW11) Antibody
20-abx320424	Abbexa	EUR 300.00 EUR 244.00	100 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 4 (FBXW4) Antibody
20-abx320507	Abbexa	EUR 300.00 EUR 244.00	100 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 12 (FBXW12) Antibody
20-abx307935	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 7 (FBXW7) Antibody
20-abx317508	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 4 (FBXW4) Antibody
20-abx322289	Abbexa	EUR 300.00 EUR 244.00	100 ul 50 ul
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 2 (FBXW2) Antibody
abx432681-200ul	Abbexa	200 ul	EUR 384
Shipped within 1-3 working days.

F-Box And WD Repeat Domain Containing 2 (FBXW2) Antibody
20-abx312212	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 5 (FBXW5) Antibody
20-abx313725	Abbexa	EUR 411.00 EUR 1845.00 EUR 599.00 EUR 182.00 EUR 300.00	100 ug 1 mg 200 ug 20 ug 50 ug
Shipped within 5-10 working days.

F-Box And WD Repeat Domain Containing 11 (FBXW11) Antibody
abx233052-100ug	Abbexa	100 ug	EUR 481
Shipped within 5-12 working days.

F-Box And WD Repeat Domain Containing 12 (FBXW12) Antibody
abx233053-100ug	Abbexa	100 ug	EUR 551
Shipped within 5-12 working days.

F-Box And WD Repeat Domain Containing 2 (FBXW2) Antibody
abx233054-100ug

Proteogenomics: From next-generation sequencing (NGS) and mass spectrometry-based proteomics to precision medication.

Preanalytic Variables and Tissue Stewardship for Reliable Next-Generation Sequencing (NGS) Clinical Analysis.

New Challenges in Tumor Mutation Heterogeneity in Advanced Ovarian Cancer by a Targeted Next-Generation Sequencing (NGS) Approach.

Next-generation sequencing of immunoglobulin gene rearrangements for clonality evaluation: a technical feasibility research by EuroClonality-NGS.

Universal DNA Marker (100 bp ~ 10,000 bp)

Universal DNA Marker (100 bp ~ 10,000 bp)

Methylamp Universal Methylated DNA Kit

Methylamp Universal Methylated DNA Preparation Kit

100 BP DNA LADDER, 500UL PER KIT

1 KB DNA LADDER, 500UL PER KIT

VAHTS Universal DNA Library Prep Kit for MGI

VAHTS Universal DNA Library Prep Kit for MGI

100bp DNA Marker

100bp DNA Marker

1Kb DNA Marker

1Kb DNA Marker

2K DNA Marker

5K DNA Marker

15K DNA Marker

1Kb DNA Marker

100bp DNA Marker

DL5000 DNA Marker

DL5000 DNA Marker

DL15000 DNA Marker

DL15000 DNA Marker

VAHTS Universal DNA Library Prep Kit for Illumina V3

VAHTS Universal DNA Library Prep Kit for Illumina V3

VAHTS Universal Pro DNA Library Prep Kit for Illumina

VAHTS Universal Pro DNA Library Prep Kit for Illumina

VAHTS Universal Plus DNA Library Prep Kit for Illumina

VAHTS Universal Plus DNA Library Prep Kit for Illumina

VAHTS Universal DNA Library Prep Kit for Ion Torrent

VAHTS Universal DNA Library Prep Kit for Ion Torrent

VAHTS Universal Pro DNA Library Prep Kit for MGI

VAHTS Universal Pro DNA Library Prep Kit for MGI

VAHTS Universal Plus DNA Library Prep Kit for MGI

VAHTS Universal Plus DNA Library Prep Kit for MGI

UNIVERSAL PLATFORM

1Kb Plus DNA Marker

DL2000 Plus DNA Marker

DL2000 Plus DNA Marker

Linear Kinetoplast DNA Marker

Decatenated Kinetoplast DNA Marker

Relaxed pRYG DNA Marker

Linear pRYG DNA Marker

1 Kb Ladder DNA Marker

100 bp Ladder DNA Marker

50 bp Ladder DNA Marker

Universal Coating Solution

Universal Detachment Solution

Universal Spring Platform

Universal Neutralization Buffer

UNIVERSAL BEER AGAR

UNIVERSAL BEER AGAR

UNIVERSAL BEER AGAR

UNIVERSAL PREENRICHMENT BROTH

UNIVERSAL PREENRICHMENT BROTH

UNIVERSAL PREENRICHMENT BROTH

Universal qPCR Mixture

VAHTS Universal DNA Library Prep Kit for Illumina V3 (PCR-Free)

VAHTS Universal DNA Library Prep Kit for Illumina V3 (PCR-Free)

Image Green? 100 bp DNA Marker

Image Green? 1 kb DNA Marker

50-500bp Low Range DNA Marker

500-10000bp DNA Marker, Original Form

500-10000bp DNA Marker, Original Form

100-1500bp DNA Marker, Original Form

100-1500bp DNA Marker, Original Form

100-1500bp DNA Marker, Original Form

100-1500bp DNA Marker, Original Form

2K Plus DNA Marker (8 linear double-stranded DNA bands)

2K Plus DNA Marker (9 linear double-stranded DNA bands)

100bp Plus DNA Marker (12 linear double-stranded DNA bands)

100bp Plus DNA Marker (14 linear double-stranded DNA bands)

Universal Casein Diluent/Blocker

5min Universal Ligation Mix

5min Universal Ligation Mix

PCR plate-foil universal

PCR plate-foil universal

Universal Full Growth Medium